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The starting XV shows nine changes to the side that defeated Connacht at the Arms Park a fortnight ago. A new back-row sees Xavier Rush, Robin Sodwen-Taylor and Maama Molitika at return. While in the front row, Rhys Thomas starts for the first time and is joined by Gary Powell.
In the backs Jamie Roberts returns to the wing and there is a new partnership at half back, with Jason Spice and Nicky Robinson both returning to the team. Gareth Thomas starts for the first time for the Cardiff Blues at inside centre.
Speaking ahead of the match, Cardiff Blues Director of rugby David Young said, "Sale are one of the strongest teams in the English league and we know they will come here to play some attractive rugby."
"They have some real star players that can cause us problems if we are not right. If we can get a performance like we did against Gloucester at the start of the season we can get the result."
Tickets for the Cardiff Blues v Sale Sharks match are available to purchase on-line or by calling the Ticket Office on 029 2030 2030.
Cardiff Blues
15 Ben Blair 14 Tom James 13 Tom Shanklin 12 Gareth Thomas 11 Jamie Roberts 10 Nicky Robinson 9 Jason Spice
8 Xavier Rush (c) 7 Robin Sowden-Taylor 6 Maama Molitka 5 Paul Tito 4 Deiniol Jones 3 Gary Powell 2 T Rhys Thomas 1 Gethin Jenkins
16 John Yapp 17 Gareth Williams 18 Robert Sidoli 19 Ben White 20 Richie Rees 21 Nick Macleod 22 Rhys Williams |